John M Kane Selected Research

ziprasidone (Geodon)

9/2015	Neuromotor Adverse Effects in 342 Youth During 12 Weeks of Naturalistic Treatment With 5 Second-Generation Antipsychotics.
3/2014	Completed and attempted suicides among 18,154 subjects with schizophrenia included in a large simple trial.
12/2013	Early nonresponse determined by the clinical global impressions scale predicts poorer outcomes in youth with schizophrenia spectrum disorders naturalistically treated with second-generation antipsychotics.
4/2012	Ziprasidone and the corrected QT interval: a comprehensive summary of clinical data.
6/2011	QT interval duration and dispersion in children and adolescents treated with ziprasidone.
2/2011	Comparative mortality associated with ziprasidone and olanzapine in real-world use among 18,154 patients with schizophrenia: The Ziprasidone Observational Study of Cardiac Outcomes (ZODIAC).
4/2009	Akathisia: an updated review focusing on second-generation antipsychotics.
5/2008	Efficacy and safety of donepezil in patients with schizophrenia or schizoaffective disorder: significant placebo/practice effects in a 12-week, randomized, double-blind, placebo-controlled trial.
1/2008	The Ziprasidone Observational Study of Cardiac Outcomes (ZODIAC): design and baseline subject characteristics.
1/2007	Does antipsychotic polypharmacy increase the risk for metabolic syndrome?

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John M Kane Research Topics

Disease

211	Schizophrenia (Dementia Praecox) 06/2022 - 01/2002
68	Psychotic Disorders (Schizoaffective Disorder) 01/2022 - 09/2002
26	Weight Gain 10/2021 - 09/2002
19	Treatment-Resistant Schizophrenia 01/2022 - 01/2002
18	Tardive Dyskinesia 01/2020 - 01/2002
17	Neoplasms (Cancer) 01/2022 - 01/2002
17	Psychomotor Agitation (Akathisia) 01/2020 - 08/2003
16	Bipolar Disorder (Manic Depressive Psychosis) 01/2018 - 07/2002
11	Mental Disorders (Mental Disorder) 10/2019 - 06/2005
10	Melanoma (Melanoma, Malignant) 01/2022 - 09/2006
9	Mood Disorders (Mood Disorder) 12/2020 - 01/2006
8	Obesity 03/2022 - 01/2003
8	Sarcoma (Soft Tissue Sarcoma) 09/2021 - 07/2004
8	Substance-Related Disorders (Drug Abuse) 01/2021 - 01/2003
8	Dyskinesias (Dyskinesia) 01/2020 - 03/2004
8	Metabolic Syndrome (Dysmetabolic Syndrome X) 12/2014 - 06/2005
7	Body Weight (Weight, Body) 01/2020 - 09/2002
7	Sleep Initiation and Maintenance Disorders (Insomnia) 01/2020 - 04/2008
6	Agranulocytosis (Granulocytopenia) 03/2022 - 04/2011
6	Inflammation (Inflammations) 03/2022 - 04/2006
6	Neuroleptic Malignant Syndrome 10/2021 - 02/2012
5	Myocarditis (Carditis) 03/2022 - 08/2004
5	Hypertension (High Blood Pressure) 01/2022 - 01/2003
5	Drug Hypersensitivity Syndrome 01/2022 - 08/2020
5	Parkinsonian Disorders (Parkinsonism) 06/2019 - 08/2003
5	Mania (Manias) 11/2017 - 09/2003
5	Disease Progression 10/2017 - 09/2006
5	Neoplasm Metastasis (Metastasis) 01/2017 - 09/2002
5	Cognitive Dysfunction 01/2016 - 05/2006
5	Coronary Disease (Coronary Heart Disease) 09/2011 - 04/2006
4	Major Depressive Disorder (Major Depressive Disorders) 05/2022 - 03/2013
4	Drug-Related Side Effects and Adverse Reactions 03/2022 - 01/2020
4	Dementia (Dementias) 01/2022 - 10/2012
4	Sialorrhea 01/2021 - 07/2012
4	Sleepiness 01/2021 - 01/2011
4	Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor) 12/2020 - 01/2009
4	Hallucinations (Hallucination) 01/2020 - 10/2005
4	Tremor (Tremors) 01/2020 - 04/2008
4	Dyslipidemias (Dyslipidemia) 12/2014 - 11/2008
3	Hyperthermia 01/2022 - 07/2013
3	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 10/2007
3	Hypersensitivity (Allergy) 09/2021 - 06/2018
3	COVID-19 12/2020 - 01/2020
3	Infections 01/2020 - 11/2002
3	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 12/2019 - 10/2009
3	Neutropenia 01/2016 - 02/2012
3	Cardiac Sudden Death (Sudden Cardiac Arrest) 12/2015 - 04/2006
3	Headache (Headaches) 05/2015 - 11/2010
3	Prediabetic State (Prediabetes) 12/2014 - 08/2008
3	Insulin Resistance 12/2014 - 01/2007
3	Hyperprolactinemia 08/2014 - 10/2009

Drug/Important Bio-Agent (IBA)

167	Antipsychotic Agents (Antipsychotics)IBA 05/2022 - 01/2002
49	Clozapine (Clozaril)FDA LinkGeneric 03/2022 - 01/2002
39	Olanzapine (Zyprexa)FDA Link 06/2019 - 01/2003
37	Risperidone (Risperdal Consta)FDA LinkGeneric 01/2021 - 01/2003
31	Aripiprazole (Abilify)FDA Link 06/2017 - 09/2002
20	Pharmaceutical PreparationsIBA 03/2022 - 10/2005
16	ziprasidone (Geodon)FDA Link 09/2015 - 01/2003
15	Haloperidol (Haldol)FDA LinkGeneric 12/2015 - 05/2002
11	ProlactinIBA 10/2021 - 09/2002
10	Quetiapine Fumarate (Seroquel)FDA Link 06/2019 - 01/2007
8	Cholinergic Antagonists (Anticholinergics)IBA 10/2021 - 08/2003
8	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 01/2003
8	Dopamine (Intropin)FDA LinkGeneric 01/2020 - 05/2012
7	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2010
6	Silver Sulfadiazine (SSD)FDA LinkGeneric 10/2021 - 01/2018
6	Antidepressive Agents (Antidepressants)IBA 09/2021 - 04/2007
6	Polytetrafluoroethylene (Teflon)FDA Link 01/2021 - 01/2016
5	LithiumIBA 01/2022 - 07/2002
5	Serotonin (5 Hydroxytryptamine)IBA 01/2020 - 01/2012
5	LipidsIBA 01/2020 - 01/2003
5	valbenazineIBA 01/2019 - 01/2017
4	BenzodiazepinesIBA 10/2021 - 07/2010
4	Paliperidone Palmitate FDA Link 03/2019 - 11/2010
4	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2018 - 04/2009
4	brexpiprazoleIBA 12/2017 - 05/2015
4	Lurasidone Hydrochloride FDA Link 12/2016 - 01/2011
4	Triglycerides (Triacylglycerol)IBA 12/2014 - 01/2007
4	HDL CholesterolIBA 09/2011 - 04/2006
3	Valproic Acid (Depakote)FDA LinkGeneric 03/2022 - 04/2009
3	Anticonvulsants (Antiepileptic Drugs)IBA 01/2022 - 01/2017
3	lumateperoneIBA 01/2021 - 01/2016
3	Dopamine Receptors (Dopamine Receptor)IBA 01/2020 - 10/2007
3	Biological ProductsIBA 01/2018 - 04/2011
3	Insulin (Novolin)FDA Link 11/2016 - 02/2013
3	Imatinib Mesylate (Gleevec)FDA Link 06/2014 - 01/2009
3	DysbindinIBA 05/2006 - 11/2004
2	N-Methyl-3,4-methylenedioxyamphetamine (MDMA)IBA 06/2022 - 01/2021
2	Dihydrotachysterol (AT 10)IBA 05/2022 - 04/2010

Therapy/Procedure

33	Injections 01/2022 - 01/2003
23	Therapeutics 05/2022 - 07/2002
17	Secondary Prevention 05/2022 - 01/2003
15	Drug Therapy (Chemotherapy) 01/2018 - 01/2002
9	Radiotherapy 09/2021 - 01/2002
6	Patient Readmission 05/2022 - 04/2002
6	Polypharmacy 12/2019 - 01/2007
5	Hyperthermic Intraperitoneal Chemotherapy 01/2022 - 06/2007
3	Lymph Node Excision (Lymph Node Dissection) 04/2019 - 12/2009
3	Neoadjuvant Therapy 01/2018 - 04/2015
3	Time-to-Treatment 05/2016 - 10/2005